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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41225da4090da7fa9b0d32abb790712e78db584576698c921c214f5f059f1d0a' 
  AND token = 'fww0Axa5heBzv97LO0A+/bXZuY6CJ5LcNJASQDAMx7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}