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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28e1496fe8ef768b94c70036a6f7245f56f0721cd616ddf6633797e6405bc9b8' 
  AND token = 'WWrHINwMAJRhCv5t6Fe0PpM68N9P8ObBDWTPmG70gHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}