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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d6294f4dc12bf8105346f4a20026e350b9fe853ccc1b7a00f7596f4e560836e' 
  AND token = 'r5qwYe1ARJJ4XdL7RrUXhhMK56x8rD8EAJby+czGFks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}