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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f145b6d6443aeebfc995f8ce18d7868d7500d548d254caf5ab6b43a52ce726ed' 
  AND token = 'EeIUVSjU9Hze7zUkfKwrxAvkDMLj7dTh7grNqYfZPzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}