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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8587df944b7602a26701b0ab919d87d948fda50a19fa48d141581d2a4060392' 
  AND token = 'SLMtF3vXLULM9A50OZ+xfRFvkOyjMxcnh53j7YFZXRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}