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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00c65ca1eba8d485e1e5e30d9b5a5dafe7736f26a8eac270c70ec5f8601b762e' 
  AND token = 'II9UgolSY5E39mV/XlkjX5H4PpI93wOPnUrDYqPNZFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}