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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1df65d75086f084deba5945a6409e2cd32aed0424f1e9a0bee5c4d6f139577f' 
  AND token = 'WdLay3rQQHgHEUCqOCx86RaVMQGKmmg94LMtc1dSCZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}