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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b1d469b0e3432187c7b7d47724d78a843a1429f72282811bf8d068d911c3f29' 
  AND token = 'ybU/3TaLeXyt0PktBlmuvJq0EmEMTUWl3Rbo5tTNeh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}