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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c1b5a68b32585bde6b7e8c0b2c2e768d35da8f7b2640734f031f574d8e86412' 
  AND token = '1kV0fGVvXuIS8p1FON860LGbOTIA5fediv25FJR/8+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}