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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8837137e9bc1d6d17c3d757a8d15defc643d7c139d7de9d45299c48f7f2a9676' 
  AND token = 'Ah/UfFPvKAqgeUlfY5+n+ejUFxoureZ2HnWnv8Aet1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}