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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ade05aee987b0a1665dbd473c23bfd574635bf7981c507250003b66ed992dedb' 
  AND token = 'CsG+p1JToFzmza0PpAgD5+bf2pDL/Z48ZSEfHB3f/sI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}