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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09c1de08073821a11aa1a07994113091736c62181257a19fd0da1c1cc5f9a63a' 
  AND token = 'kHJBNCIC0XG7265mlaE3nzaLY7E+8vRHf75fhdewSho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}