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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9aac2a620bc246bf13e0270a6089d64da1f6f5d964410e5275d397aaaa842b5d' 
  AND token = 'XRyOhNS/fBu8z+91/dmJwlrx99qoxPrCs3qWMSsA4hY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}