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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5305be879d131e56bc0d877354021f602e3d635cfcd5c0813f81c3e148a89dc7' 
  AND token = 'NkxAqYwgP/gQ2tf7gEeyVIPFIFBRxYp4lV0h0TE3CNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}