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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e39b3ff34a93983cbba1b0e00411633e9ec61ef11e0f749859ef9c879236be41' 
  AND token = 'MdQQc5Kl0umJvyH8athNz+BKo9sFNVXztu2gqc4DnSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}