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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e12c09e95f79c3748624ca0c312f2b9b4dbb8ce363cf06fc5cb167105c203336' 
  AND token = '0F0vAZ6XklubAvIJGpPad6/RzABCQDnou37cGeS0UFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}