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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3efa5e16e557e3568790a4381377801b8ef9c88a54a833ca60b682cde9a9bfa0' 
  AND token = 'e1k4W6nbtGDrk7QV8UkHfLCCZbWGvKCYN9qk4iKsIzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}