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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b972401db70126354254b36519d4b110ec81b93cfce04a9fd6db0c509e8a0823' 
  AND token = 'weGlepb7KLgpFGTAZ9wGWDiYr2OqWMiKAD/wR9/dZ3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}