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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8369f6f1b9befdfa00593f4748f3d37b166f337cc807f77d51a2d3b372e588e' 
  AND token = 'CxnJj3OtybOL/08MxsdvU+COth9na15+leV2hUsqj20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}