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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'effd693f6f3617977da3715d59fe6918c71ade1c95899ac9b9fc4bb3ee768124' 
  AND token = '+ISGrAOQ8dy7R+VEsVJZ1nnAe6x+Z/a+QxB8oX8ruwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}