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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36546ee363267a53033e5ecc3f21524653aa325e3cc0f1113ffea64996f95ae3' 
  AND token = 'RE1I/Je6mq2bH7oVEvs5/MVzixeIRkI6Wlqj9Hf1pGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}