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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e650a8cc51a8a7919b5e762e9529ffca64cb3a64b457425e291c2b3588b3930e' 
  AND token = 'R157G10HNYKifRjL+fbFjq7V047W6swITFUa7Om+Y/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}