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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a58ce787098a668fe399e4ffbf4b089f24c56f5ec9cff3efb8f96175f37b0b6a' 
  AND token = 'ohdPY7TaCkTmRFCzg2wx1rd/HZ0+udHpAQpeosiqfl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}