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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1478f4d6ee0f8aa2874488a4fcf82b66836c6b861712de721d1076fe84f6ab4d' 
  AND token = 'imAvqgU7YhW8dH8MSJSikdWBgRMbQNhWI47NOCWEQ1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}