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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48cd44788908d2ff43d6ea01c0136caede9c70cf5027b3116ee606dce8ea3792' 
  AND token = 'eTLXwlzbHQnWtNwnw5RGI8ZF1dnzVkg4zaR/Obsxd0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}