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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64be976e833963c4d0a82d379a813f4e901b610adb0543292e4f15ca6f71c851' 
  AND token = 'mXMqPp+U+voJU4pt6V+sHybmxUUC2Mdc4/ReQ57Hq4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}