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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef43baa5b693799f195deaae57e056c662ebe0ce0c453fd08ec6b1f364c13ce7' 
  AND token = 'cQ2W0fB8934UUZ06IRJDcacLTJZcm3Do50lMOUWMnRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}