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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da84491d35faaf1c722fa8dbaef4ba54db35975a10c85e08a3f33153160e5c78' 
  AND token = 'MlgOFTJaQv8ntQoa4FaPjkkco8GKgGZL5cwJ01CSLiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}