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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f864d0f611e2b12a295adc0f433f2c91081075898a48f293b3a5f4e4e7dbfcc' 
  AND token = 'ZYrdvxoxaYRmTY4v9ItGkG3hrI6Mz6OQ06NCUK8CZfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}