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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb6f2f16e76acd46f55532e5cea5b24bc100ed4b6ddfaa84e047e32bcf4e9859' 
  AND token = 'CCBYp6KnV0alEXrAHiH9qtlwP29Dt0dwMV4BBhADeGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}