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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16d33da8b85bb4feb50e33b03d9635291d5305aaffe20fe3e4ba501d33f5af9e' 
  AND token = 'D48j+JB+YiWAF68m4PD0yRPTXqOaw0XZJ49wF5pZDD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}