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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f5213cdfabece080ea0c9202fd6e1f9edb9f1e7344d2d3579f33ce516c40e34' 
  AND token = 'LXCJOUfGh1MauCAp+H9c98nG/RMBNUWp9UKT6Ds7Jtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}