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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22bef530f26e5d2224812ef226c640cd57d1a6241a9ef6d068e0994b8aa052ee' 
  AND token = 'CyMOCgmDPrWO+Qq8KHtn3B7G82WERxTPW5GrlkF41pM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}