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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25c1064b13eccb1cfc2d5f54f96fc8819186e9a0ede6edd4ed9c08ea3a77f125' 
  AND token = 'FxegTPjD7fANkxlGYBnd3c159o+/oMYhrm/Tm76go2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}