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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d5b1e2c424e58f41865414ac507784e88da989a8dbcc39869c837c9d70d6dd0' 
  AND token = 'M10T/JcbUqSik0XT3MOXxZbNo3KXEwC+TpSrp2RvWPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}