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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36be5d7dcc87256e75023cb3ce1e27dfa8239995bd0c35fd4cf6bdb08cade749' 
  AND token = 'azMRSsgABm+aPwSPUg+UdrYO2A/mXVHJRMUmo8M99YM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}