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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d924e33270c2d5e8a1dfd7ecac833aa7f8b06484c6a99090cda2439e78b5f23' 
  AND token = '4+KcoX40Moz7VBCixofpW+ESKir0vkWGMFeS0DhxOy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}