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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed6a3dcaad33036387573e1efec5bd53a5bcdc121d2060a138431fedc5bd5678' 
  AND token = '0cmlAmd7z1UEXRn431Z1gG+9RHS/EH/v2hWFf1O8YIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}