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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b69a9ef1c4288579a32ce326bbc458fe190dbf83c9716accc0799451b3ea653' 
  AND token = '0XUGa01sgVLQk+/vWa7vWpMZm240SgdXFK4UayVXjfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}