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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9df56597cabfdca12aeb45dc31280eb660f57d69314d4552996db73f2ccc36cf' 
  AND token = '/uuIAAxDOxFZzQcLXUWDAwzqOEiCGWqC9cyPXXSFGIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}