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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54091b9232b36600f7512a25a85638482bc9ba7dc77952256a6887620c4130fc' 
  AND token = 'lauLW1DJO/8OT3Hcn+Ia5637Jcc9ZYmAnSUMXyQHZI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}