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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '782d4480b1f6edcadda35627b455c8816ca65801078b7cbc0a3548f1ac624fb1' 
  AND token = 'IgevwUwjGaSLHkE5dxVcuVc/kyW/yp8fk8AFe4hTv6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}