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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c441947bb7212ee7d90f233032f0c58609cb8aeba89a7263212b6a12bea3ba46' 
  AND token = 'W/6o/gWTuGJP7BrEB7IO3LtNhDbBDWkY41f0eqhDRQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}