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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e001f36a2eeab90f4ce19b5847c6923d9b71779d5660c0c1a1a218791069e09' 
  AND token = 'VBJUMcMOGo7NtJV1Xr0kw0Kw/Isf+85cEqTcioCQaCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}