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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8c0de830493644226622b003503d758982c502f642529a2e3a6c57b3e75f9cf' 
  AND token = '2FcL7q+Odh9Ftc6ndms6iIy7wPnv4QZZEoJx3wxUIss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}