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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ff6f583a70a7be5dd47853b0d6a60f021c0699082f63c5bd22ed4a274f7bd9b' 
  AND token = '1PNbgWiZWidNZKTG+UxSJgEjSn2IWS8f1bGtwXl8Gvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}