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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ae21dea28c4959971240f3d9dd8862fb1a4cdd87b8f90a02c62a8f35743d2c8' 
  AND token = 'nymTmyCddoJn7X+asaqa9KBTrX5AyBLlRWpeD5jHTQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}