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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e06a7462615c2b460a6cdd79183f0a985d7ef9c1d6b2a8da444185499b48e32' 
  AND token = 'qZeC1ER+0saJZtVWQTl1VPsLqWELk/0WYoDlQssFgG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}