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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '365392f277202f6713e21979780a09dc275f6995a3ca9056bd3b5cf9a9f30dc1' 
  AND token = 'C/yG30G3B5lsdfthLQnfsBKEDsGzXtoNVUz6rFMe50c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}