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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abfc0a6decc203680dd6b3ef82c049e56e9ffd7844f8c14f7158f7028e62d437' 
  AND token = 'tTlbld5s6CC9L0yE8MW27MprFOs4NdIPKMfwLDQIOr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}